Safety data sheet for N,N-Dimethylformamide
CAS 68-12-2
This is the free preview of a draft SDS for N,N-Dimethylformamide — Sections 1, 2 and 9, generated from the sources named below. The full 16-section draft, with your own company in Section 1, is $5 per document.
Typically documented by: Laboratory and industrial solvent.
Draft safety data sheet — preview
Sections 1, 2, 9 of 16
- CAS number
- 68-12-2
- Molecular formula
- C3H7NO
- Molecular weight
- 73.09 g/mol
- Signal word
- Danger
Hazard classification
- GHS02 — Flammable
- GHS06 — Acute toxicity
- GHS08 — Serious health hazard
- GHS07 — Health hazard — irritant
- H226: Flammable liquid and vapor.
- H312: Harmful in contact with skin.
- H332: Harmful if inhaled.
- H360D: May damage the unborn child.
Section 1 — Identification
1.1 Product identifier
Product identifier: Dimethylformamide
Chemical name (IUPAC): N,N-dimethylformamide
CAS number: 68-12-2
PubChem CID reference: 6228
Synonyms: N,N-DIMETHYLFORMAMIDE; Dimethylformamide; Dimethyl formamide; N-Formyldimethylamine; Formamide, N,N-dimethyl-; Dimethylformamid; DMFA; N,N-Dimethyl formamide; Formyldimethylamine; Dimetilformamide
Section 2 — Hazards Identification
2.1 Classification of the substance or mixture
Classification basis: OSHA 29 CFR 1910.1200 Appendix A, aligned to the GHS Rev. 7 hazard classes this sheet resolves: Flam. Liq. 3, Acute Tox. 4 (Dermal), Acute Tox. 4 (Inhalation).
Classification: Flammable Liquid, Category 3 (Flam. Liq. 3) [H226]
Classification: Acute Toxicity, Category 4 — Dermal (Acute Tox. 4 (Dermal)) [H312]
Classification: Acute Toxicity, Category 4 — Inhalation (Acute Tox. 4 (Inhalation)) [H332]
2.2 Label elements
Signal word: Danger
GHS pictograms: GHS02 (Flammable), GHS06 (Toxic), GHS08 (Health Hazard), GHS07 (Exclamation)
Hazard statement: H226: Flammable liquid and vapor.
Hazard statement: H312: Harmful in contact with skin.
Hazard statement: H332: Harmful if inhaled.
Hazard statement: H360D: May damage the unborn child.
Precautionary statement: P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
Precautionary statement: P264+P265: Wash hands thoroughly after handling. Do not touch eyes.
Precautionary statement: P280: Wear protective gloves, protective clothing, eye protection, face protection, and hearing protection.
Precautionary statement: P303+P361+P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
Precautionary statement: P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
Precautionary statement: P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Section 9 — Physical and Chemical Properties
9.1 Information on basic physical and chemical properties
Physical form: Liquid
Appearance: Colorless to very slightly yellow liquid
Odor: Fishy odor
Boiling point: 76°C (169°F) at 1013 hPa
Melting point: -60.3°C (-77°F)
Flash point: 58°C (136°F) closed cup
Density: 0.9445 at 25 °C/4 °C
Vapor pressure: 4.9 hPa at 25°C
Water solubility: Miscible
Log Pow (log Kow): -1.01
Vapor density: 2.51 (air = 1)
Lower explosive limit: 2.2% (v/v in air)
Upper explosive limit: 15.2% (v/v in air)
Auto-ignition temperature: 440°C (824°F)
Viscosity: 0.8 cP at 25°C
pH: pH = 6.7 (0.5 molar solution in water)
Occupational exposure limits for N,N-Dimethylformamide
The airborne limits on public record in the United States. These are transcribed from the tables named in each row, not derived. The full draft puts them in Section 8 with the control and PPE guidance.
OSHA PEL — TWA (8 h)
10 ppm (30 mg/m³)
OSHA Annotated PEL Table Z-1
NIOSH REL — TWA (up to 10 h)
10 ppm
OSHA Annotated PEL Table Z-1 (NIOSH REL column)
Where each value came from
- Odor — Hazardous Substances Data Bank (HSDB)
- Verschueren, K. Handbook of Environmental Data on Organic Chemicals. Volumes 1-2. 4th ed. John Wiley & Sons. New York, NY. 2001, p. V1 914
- View the record
- Boiling point — Hazardous Substances Data Bank (HSDB)
- O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Cambridge, UK: Royal Society of Chemistry, 2013, p. 590
- View the record
- Melting point — Hazardous Substances Data Bank (HSDB)
- Haynes, W.M. (ed.). CRC Handbook of Chemistry and Physics. 94th Edition. CRC Press LLC, Boca Raton, FL: 2013-2014, p. 3-210
- View the record
- Flash point — Hazardous Substances Data Bank (HSDB)
- Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001), p. V4 1318
- View the record
- Density — Hazardous Substances Data Bank (HSDB)
- Same reference as boiling point above.
- View the record
- Water solubility — Hazardous Substances Data Bank (HSDB)
- Same reference as boiling point above.
- View the record
- Log Pow (log Kow) — Hazardous Substances Data Bank (HSDB)
- Hansch, C., Leo, A., D. Hoekman. Exploring QSAR - Hydrophobic, Electronic, and Steric Constants. Washington, DC: American Chemical Society., 1995, p. 6
- View the record
- Viscosity — Hazardous Substances Data Bank (HSDB)
- Marsella JA; Dimethylformamide. Kirk-Othmer Encyclopedia of Chemical Technology. (1999-2014). New York, NY: John Wiley & Sons. Online Posting Date: 18 Jan 2013
- View the record
A value with no row here was assembled from more than one record, so no single record is credited for it. The draft you buy carries this table as an appendix covering all 16 sections.
Sources
- ECHA C&L Inventory — harmonised CLP entry
- Hazardous Substances Data Bank (HSDB)
- OSHA Annotated PEL Table Z-1
- OSHA Annotated PEL Table Z-1 (NIOSH REL column)
- PubChem — GHS classification
- PubChem — compound record
- PubChem — names and identifiers
- PubChem — regulatory information
- PubChem — toxicity data
- PubChem — transport information
Sections 1.3 and 1.4 are withheld here because the supplier and emergency contact blocks carry your own company details in the draft you buy. Every draft needs review by a competent person before it is issued.
Measured values for N,N-Dimethylformamide, and where each one comes from
33 measured values for 13 properties, read from 4 public databases. On 6 properties the records differ. Each reading is shown with its own record. Follow any record to read the value at its source.
Boiling point
5 records, 76 to 153 °C
Used with vapour pressure to judge how readily the substance reaches the air you breathe.
- BP: 76 °C at 39 mm Hg; 25 °C at 3.7 mm Hg
- Hazardous Substances Data Bank (HSDB)
- 307 °F
- NIOSH Pocket Guide
- 153 °C @760 [mm Hg]
- PAC Chemical Database, U.S. Department of Energy
Melting point
4 records, -61 to -60 °C
Fixes the physical state at handling temperature, which the label and the transport class depend on.
- -78 °F
- NIOSH Pocket Guide
Flash point
4 records, 58 to 67 °C
The lowest temperature at which the liquid gives off enough vapour to ignite. It decides the GHS flammable liquid category.
- 67 °C (open cup); 58 °C (Closed cup)
- Hazardous Substances Data Bank (HSDB)
- 136 °F (58 °C)
- Hazardous Substances Data Bank (HSDB)
- 136 °F
- NIOSH Pocket Guide
Auto-ignition temperature
1 record
The temperature at which the substance ignites with no spark or flame. It sets safe surface and process temperatures.
Vapour pressure
4 records differ
The higher it is, the faster the substance evaporates into the workplace air at room temperature.
- 3.87 mm Hg at 25 °C
- Hazardous Substances Data Bank (HSDB)
- 3 mmHg
- NIOSH Pocket Guide
- 7.5 [mm Hg] @38 °C
- PAC Chemical Database, U.S. Department of Energy
Vapour density
2 records differ
Above 1 the vapour sinks and collects in pits, sumps and low enclosed spaces.
- 2.51 (Air= 1)
- Hazardous Substances Data Bank (HSDB)
Density
4 records differ
Needed to convert between mass and volume on the label, in transport papers and in a spill estimate.
- 0.9445 at 25 °C/4 °C
- Hazardous Substances Data Bank (HSDB)
- 0.9455 @25 °C
- PAC Chemical Database, U.S. Department of Energy
Solubility
3 records, each a different case
Determines spill behaviour, the right extinguishing media and the correct first-aid rinse.
- Miscible with water and most common organic solvents
- Hazardous Substances Data Bank (HSDB)
- Miscible with ethanol, ethyl ether, acetone, benzene; slightly soluble in ligroin
- Hazardous Substances Data Bank (HSDB)
- Miscible
- NIOSH Pocket Guide
Partition coefficient (log Kow)
1 record
Indicates whether the substance accumulates in fat or in water, which drives the environmental sections.
- log Kow = -1.01
- Hazardous Substances Data Bank (HSDB)
Viscosity
1 record
Governs how far a spill spreads and how fast it soaks into a surface or a sorbent.
- 0.802 cP at 25 °C
- Hazardous Substances Data Bank (HSDB)
pH
1 record
Drives the skin and eye corrosion classification for solutions, alongside the corrosivity data.
- pH = 6.7 (0.5 molar solution in water)
- Hazardous Substances Data Bank (HSDB)
Odour
2 records, each a different case
Odour is a warning property only. Many substances are hazardous well below the concentration you can smell.
- Fishy odor
- Hazardous Substances Data Bank (HSDB)
- Faint, amine-like odor
- Hazardous Substances Data Bank (HSDB)
Decomposition temperature
1 record
The temperature at which the substance breaks down, often into products more hazardous than itself.
- Temperatures >350 °C may cause decomposition to form dimethylamine and carbon dioxide, with pressure developing in closed containers
- Hazardous Substances Data Bank (HSDB)
These are the public records read for N,N-Dimethylformamide, published here unchanged. Where two records disagree, the draft you buy states the value and names the record behind it, so a reviewer can see what was chosen. Every draft needs review by a competent person before it is issued.
Get the full draft SDS for N,N-Dimethylformamide
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